Clear, thoughtful, well written. It brings together the top minds in the field, synthesize new data, and succeeds in moving the field further. They consider mood disorders from all angles. Medical causes like obesity and inflammation. Genetic. Family dynamics. And they tell you how to treat it. How to use medications more thoughtfully in this population where the evidence is often unclear; how to clarify bipolar, unipolar, and the sub threshold cases where we’re just not sure. And how to integrate a psychosocial and environmental plan into the treatment- the right one for the right age and the right diagnosis